已在New England Journal of Medicine, Clinical Cancer Research, Cancer Research等雜志發(fā)表SCI文章90余篇,影響因子總計(jì)362,被引用2335次。參與編寫中文專著3部,英文專著2部。
出版專著(Book Chapter):
1. Epigenetics and Tumor Suppressor Genes
by MingZhou Guo, XueFeng Liu and WeiMin Zhang in the book "Tumor Suppressor Genes" edited by Yue Cheng, ISBN 978-953-307-879-3, InTech, February 2, 2012
2. Molecular Biology Character of Esophageal Cancer
by Mingzhou Guo, Yan Jia and Wenji Yan in the book "Esophageal Cancer - Cell and Molecular Biology, Biomarkers, Nutrition and Treatment" edited by Ferdous Rastgar Jazii, ISBN 978-953-51-0223-6, InTech, March 3, 2012
發(fā)表英文論文:
2012
1. Liu X, Zhang X, Zhan Q, Brock M, Herman JG, Guo M. CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. Cancer Biol Ther. 2012 Oct 1;13(12). [Epub ahead of print] (correspondence)
2. Yin D, Jia Y, Yu Y, Brock MV, Herman JG, Han C, Su X, Liu Y, Guo M. SOX17 methylation inhibits its antagonism of Wnt signaling pathway in lung cancer. Discov Med. 2012 Jul;14(74):33-40. (correspondence)
3. Jia Y, Yang Y, Brock MV, Zhan Q, Herman JG, Guo M. Epigenetic Regulation of DACT2, A Key Component of the Wnt Signaling Pathway in Human Lung Cancer. J Pathol. 2012 Jul 18. doi: 10.1002/path.4073. [Epub ahead of print] (correspondence)
4. Yan Jia,Yunsheng Yang, Qimin Zhan, Hongbin Zhu, Yuanzi Yu, James G. Herman and Mingzhou Guo MicroRNA-141 and Methylation Regulation of WNT Signal Pathway by Suppressing SOX17 in Esophageal Cancer. Journal of Molecular Diagnosis. 14 (6): 2012. (In Press) (correspondence)
5. Yan WJ, Guo MZ, Yang YS. [The role of hypermethylation in promoter region of ubiquitin carboxyl-terminal hydrolase L1 in human esophageal cancer]. Zhonghua Nei Ke Za Zhi. 2012 May;51(5):390-3.
6. Chen YH, Wu ZQ, Zhao YL, Si YL, Guo MZ, Han WD. FHL2 inhibits the Id3-promoted proliferation and invasive growth of human MCF-7 breast cancer cells. Chin Med J (Engl). 2012 Jul;125(13):2329-33.
7. Chen XY, He QY, Guo MZ. XAF1 is frequently methylated in human esophageal cancer. World J Gastroenterol. 2012 Jun 14;18(22):2844-9. (correspondence)
8. Jia Y, Yang Y, Brock MV, Cao B, Zhan Q, Li Y, Yu Y, Herman JG, Guo M. Methylation of TFPI-2 is an early event of esophageal carcinogenesis. Epigenomics. 2012 Apr;4(2):135-46. (correspondence)
9. Deng YZ, Yao F, Li JJ, Mao ZF, Hu PT, Long LY, Li G, Ji XD, Shi S, Guan DX, Feng YY, Cui L, Li DS, Liu Y, Du X, Guo MZ, Xu LY, Li EM, Wang HY, Xie D. RACK1 Suppresses Gastric Tumorigenesis by Stabilizing the β-Catenin Destruction Complex. Gastroenterology. 2012 Apr;142(4):812-823.e15. Epub 2012 Jan 10.
10. Yu Y, Yin D, Hoque MO, Cao B, Jia Y, Yang Y, Guo M. Tumour Biol. AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer. Tumour Biol. 2012 Apr;33(2):307-14.. (correspondence)
11. Gong Y, Yang YS, Zhang XM, Su M, Wang J, Han JD, Guo MZ. ABO blood type, diabetes and risk of gastrointestinal cancer in northern China. World J Gastroenterol. 2012 Feb 14;18(6):563-9. (correspondence) .
2011
12. Chen T, Yan F, Qian J, Guo M, Zhang H, Tang X, Chen F, Stoner GD, Wang X. Randomized phase II trial of lyophilized strawberries in patients with dysplastic precancerous lesions of the esophagus. Cancer Prev Res (Phila). 2012 Jan;5(1):41-50. Epub 2011 Dec 1.
13. Ning B, Liu G, Liu Y, Su X, Anderson GJ, Zheng X, Chang Y, Guo M, Liu Y, Zhao Y, Nie G. 5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of transferrin receptor 1 (TfR1) and ferrochelatase (Fech) genes. J Biol Chem. 2011 Oct 28;286(43):37196-206. Epub 2011 Sep 7.
14. Jia Y, Guo M. Epigenetic changes in colorectal cancer. Chin J Cancer. 2011 Nov 4. doi: 10.5732/cjc.011.10245. [Epub ahead of print]PMID:22059907[PubMed - as supplied by publisher] (correspondence)
15. Ying Chen, Chun-min Yang, Gao-ping Mao, Qing-sen Liu and Ming-zhou Guo. Effects of simulated weightlessness on the intestinal mucosal barrier of rats. J Huazhong Univ Sci Technolog Med Sci. 2011 Feb;31(1):26-32. Epub 2011 Feb 19)
16. Hou J, Li EM, Shen JH, Qing-Zhao, Wu ZY, Xu XE, Wu JY, Qiao-Huang, Shen J, Guo MZ, Xu LY. Cytoplasmic HDPR1 is involved in regional lymph node metastasis and tumor development via beta-catenin accumulation in esophageal squamous cell carcinoma. J Histochem Cytochem. 2011 Jul;59(7):711-8. Epub 2011 Apr 27. (Co-correspondence).
17. Wang M, Cheng Z, Tian T, Chen J, Dou F, Guo M, Cong YS. Differential expression of oncogenic miRNAs in proliferating and senescent human fibroblasts. Mol Cell Biochem. 2011 Mar 17. [Epub ahead of print]
2010
18. Jia Y, Yang Y, Liu S, Herman JG, Lu F, Guo M. SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma. Epigenetics. 2010 Nov-Dec;5(8):743-9. Epub 2010 Nov 22. (correspondence)
19. Xiao-Mei Zhang and Ming-Zhou Guo . The value of epigenetic markers in esophageal cancer. Front Med China 4(4):378-84 (2010) Review. (correspondence)
20. Wang J, Zhao W, Cheng L, Guo M, Li D, Li X, Tan Y, Ma S, Li S, Yang Y, Chen L, Wang S. CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice. J Immunol. 2010 Dec 15;185(12):7654-62. Epub 2010 Nov 8.
21. Ye Zhao, Jian-Sheng Li, Ming-Zhou Guo, Bai-Sui Feng and Jin-Ping Zhang Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells in vivo and in vitro. Chin J Cancer 29(8):752-60
22. Zhao Y, Li JS, Guo MZ, Feng BS, Zhang JP, Chen XY. Effects of S-adenosylmethionine on gastric cancer cell lines SGC-7901 and BGC-823. Zhonghua Yi Xue Za Zhi. 2010 Jun 8;90(22):1559-64.
23. Zhang XL, Yang YS, Sun G, Guo MZ. Natural orifice translumenal endoscopic surgery (NOTES): current status and challenges.Chin Med J (Engl). 2010 Jan 20;123(2):244-7. Review
2009
24. Ye Y, McDevitt MA, Guo M, Zhang W, Galm O, Gore SD, Karp JE, Maciejewski JP, Kowalski J, Tsai HL, Gondek LP, Tsai HC, Wang X, Hooker C, Smith BD, Carraway HE, Herman JG. Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies. Cancer Res. 2009 Nov 1;69(21):8482-90. Epub 2009 Oct 13.
2008
25. Guo M, Ren J, Brock MV, Herman JG, Carraway HE. Promoter methylation of HIN-1 in the progression to esophageal squamous cancer. Epigenetics. 2008 Nov;3(6):336-41. Epub 2008 Nov 8.
26. Zhang W, Glöckner SC, Guo M, Machida EO, Wang DH, Easwaran H, Van Neste L, Herman JG, Schuebel KE, Watkins DN, Ahuja N, Baylin SB. Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res. 2008 Apr 15;68(8):2764-72.
27. Carraway HE, Wang S, Blackford A, Guo M, Powers P, Jeter S, Davidson NE, Argani P, Terrell K, Herman JG, Lange JR. Promoter hypermethylation in sentinel lymph nodes as a marker for breast cancer recurrence. Breast Cancer Res Treat. 2008 Apr 11. [Epub ahead of print]
28. Brock MV, Hooker CM, Ota-Machida E, Han Y, Guo M, Ames S, Glöckner S, Piantadosi S, Gabrielson E, Pridham G, Pelosky K, Belinsky SA, Yang SC, Baylin SB, Herman JG. DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med. 2008 Mar 13;358(11):1118-28.
2007
29. Guo M, House MG, Suzuki H, Ye Y, Brock MV, Lu F, Liu Z, Rustgi AK, Herman JG. Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. Int J Cancer. 2007 Sep 15;121(6):1219-26.
30. Riojas MA, Guo M, Glöckner SC, Machida EO, Baylin SB, Ahuja N. Methylation-Induced Silencing of ASC/TMS1, a Pro-Apoptotic Gene, is a Late-Stage Event in Colorectal Cancer. Cancer Biol Ther. 2007 Nov;6(11):1710-6. Epub 2007 Aug 3. ( first author equal contribution)
31. Fu B, Guo M, Wang S, Campagna D, Luo M, Herman JG, Iacobuzio-Donahue CA. Evaluation of GATA-4 and GATA-5 Methylation Profiles in Human Pancreatic Cancers Indicate Promoter Methylation Patterns Distinct from other Human Tumor Types. Cancer Biol Ther. 2007 Oct;6(10):1546-52.
32. Lu F, Chen H, Zhou C, Liu S, Guo M, Chen P, Zhuang H, Xie D, Wu S. T-type Ca(2+) channel expression in human esophageal carcinomas: A functional role in proliferation.Cell Calcium. 2008 Jan;43(1):49-58. Epub 2007 May 25.
33. Yue W, Dacic S, Sun Q, Landreneau R, Guo M, Zhou W, Siegfried JM, Yu J, Zhang L. Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter Hypermethylation. Clin Cancer Res 2007 Aug 1;13(15 Pt 1):4336-44.
2006
34. Guo M, Liu S, Lu F. Gefitinib-sensitizing mutations in esophageal carcinoma. N Engl J Med. 2006 May 18;354(20):2193-4.
35. Guo M, House MG, Akiyama Y, Qi Y, Capagna D, Harmon J, Baylin SB, Brock MV, Herman JG. Hypermethylation of the GATA gene family in esophageal cancer. Int J Cancer. 2006 Jul 5;119(9):2078-2083
36. Guo M, Ren J, House MG, Qi Y, Brock MV, Herman JG. Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus. Clin Cancer Res. 2006 Aug 1;12(15):4515-22.
37. Benzeno S, Lu F, Guo M, Barbash O, Zhang F, Herman JG, Klein PS, Rustgi A, Diehl JA. Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1. Oncogene. 2006 Oct 12;25(47):6291-303. [Epub ahead of print]
38. Guo M, Liu S, Herman, JG, Zhuang, H Lu, F. Gefitinib-Sensitizing Mutation in Esophageal Carcinoma Cell Line Kyse450. Cancer Biol Ther. 2006 Feb;5(2):152-5.
39. Hong KM, Yang SH, Guo M, Herman JG, Jen J. Semiautomatic detection of DNA methylation at CpG islands. Biotechniques. 38:354-358, 2005.
40. Yang B, House MG, Guo M, Herman JG, Clark DP. Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma. Mod Pathol. 18:412-420, 2005.
41. Liu ZM, Zhang L, Ding F, Li J, Guo M, Li W, Wang Y, Yu Z, Zhan Q, Wu M, Liu Z. 5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells. Cancer Lett. 230:271-283, 2005.
42. Brock MV, Hooker CM, Yung R, Guo M, Han Y, Ames SE, Chang D, Yang SC, Mason D, Sussman M, Baylin SB, Herman JG. Can we improve the cytologic examination of malignant pleural effusions using molecular analysis? Ann Thorac Surg. 80:1241-1247, 2005.
2004
43. Guo M, House MG, Hooker C, Han Y, Heath E, Gabrielson E, Yang SC, Baylin SB, Herman JG, Brock MV. Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res. 10: 5131-5136, 2004.
44. Guo M, Akiyama Y, House MG, Hooker CM, Heath E, Gabrielson E, Yang SC, Han Y, Baylin SB, Herman JG, Brock MV. Hypermethylation of the GATA genes in lung cancer. Clin Cancer Res. 10:7917-7924, 2004.
45. Wang JS, Guo M, Montgomery EA, Thompson RE, Cosby H, Hicks L, Wang S, Herman JG, Canto MI. DNA Promoter Hypermethylation of p16 and APC Predicts Neoplastic Progression in Barrett's Esophagus. Am J Gastroenterol. 2009 Jul 7. [Epub ahead of print]
44. Liu ZM, Ding F, Guo MZ, Zhang LY, Wu M, Liu ZH. Down regulation of retinoic acid receptor-beta(2) expression is linked to aberrant methylation in esophageal squamous cell carcinoma cell lines. World J Gastroenterol. 10:771-775, 2004.
2003
47. Yang B, Guo M, Herman JG, Clark DP. Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. Am J Pathol. 163:1101-1107, 2003. ( first author equal contribution)
48. Esteller M, Guo M, Moreno V, Peinado MA, Capella G, Galm O, Baylin SB, Herman JG. Hypermethylation associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer. Cancer Res. 6 :5902-5905, 2002.
49. House MG, Guo M, Efron DT, Lillemoe KD, Cameron JL, Syphard JE, Hooker CM, Abraham SC, Montgomery EA, Herman JG, Brock MV. Tumor suppressor gene hypermethylation as a predictor of gastric stromal tumor behavior. J Gastrointest Surg. 7:1004-1014, 2003.
50. Brock MV, Gou M, Akiyama Y, Muller A, Wu TT, Montgomery E, Deasel M, Germonpre P, Rubinson L, Heitmiller RF, Yang SC, Forastiere AA, Baylin SB, Herman JG. Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma. Clin Cancer Res. 9:2912-2919, 2003.
51. House MG, Guo M, Iacobuzio-Donahue C, Herman JG. Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Carcinogenesis. 24:193-198, 2003.
52. House MG, Herman JG, Guo MZ, Hooker CM, Schulick RD, Cameron JL, Hruban RH, Maitra A, Yeo CJ. Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms. Surgery. 134:902-908, 2003.
53. House MG, Herman JG, Guo MZ, Hooker CM, Schulick RD, Lillemoe KD, Cameron JL, Hruban RH, Maitra A, Yeo CJ. Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms. Ann Surg. 238:423-431, 2003.
54. House MG, Wistuba II, Argani P, Guo M, Schulick RD, Hruban RH, Herman JG, Maitra A. Progression of gene hypermethylation in gallstone disease leading to gallbladder cancer. Ann Surg Oncol. 10:882-889, 2003.
55. Paz MF, Fraga MF, Avila S, Guo M, Pollan M, Herman JG, Esteller M. A systematic profile of DNA methylation in human cancer cell lines. Cancer Res. 63:1114-1121, 2003.
56. Sarrio D, Moreno-Bueno G, Hardisson D, Sanchez-Estevez C, Guo M, Herman JG, Gamallo C, Esteller M, Palacios J. Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability. Int J Cancer. 106:208-215, 2003.
2002
57. Moreno-Bueno G, Hardisson D, Sanchez C, Sarrio D, Cassia R, Garcia-Rostan G, Prat J, Guo M, Herman JG, Matias-Guiu X, Esteller M, Palacios J. Abnormalities of the APC/beta-catenin pathway in endometrial cancer. Oncogene. 21:7981-90, 2002.
58. Esteller M, Fraga MF, Paz MF, Campo E, Colomer D, Novo FJ, Calasanz MJ, Galm O, Guo M, Benitez J, Herman JG. Cancer epigenetics and methylation. Science. 297:1807-1808, 2002.
59. Laiho P, Launonen V, Lahermo P, Esteller M, Guo M, Herman JG, Mecklin JP, Jarvinen H, Sistonen P, Kim KM, Shibata D, Houlston RS, Aaltonen LA. Low-level microsatellite instability in most colorectal carcinomas. Cancer Res. 62:1166-1170, 2002.
60. Caballero OL, Resto V, Patturajan M, Meerzaman D, Guo M, Engles J, Yochem R, Ratovitski E, Sidransky D, Jen J. Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1). Oncogene. 21:3003-3010, 2002.
2001
61. Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedenfalk I, Godwin AK, Trojan J, Vaurs-Barriere C, Bignon YJ, Ramus S, Benitez J, Caldes T, Akiyama Y, Yuasa Y, Launonen V, Canal MJ, Rodriguez R, Capella G, Peinado MA, Borg A, Aaltonen LA, Ponder BA, Baylin SB, Herman JG. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum Mol Genet.10:3001-3007, 2001.
62. Nacht M, Dracheva T, Gao Y, Fujii T, Chen Y, Player A, Akmaev V, Cook B, Dufault M, Zhang M, Zhang W, Guo M, Curran J, Han S, Sidransky D, Buetow K, Madden SL, Jen J. Molecular characteristics of non-small cell lung cancer. Proc Natl Acad Sci U S A. 2001.
發(fā)表中文論文:
1 18例胰腺分裂癥的臨床特點(diǎn)分析 楊帥; 張游; 李聞; 令狐恩強(qiáng); 王永華; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2015-05-20
2 表觀遺傳組學(xué)——腫瘤精準(zhǔn)治療的新靶標(biāo) 閆文姬; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2015-05-20
3 中國(guó)北方地區(qū)慢性胰腺炎的病因分析 楊帥; 令狐恩強(qiáng); 李聞; 王永華; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2015-04-20
4 表觀遺傳學(xué)調(diào)控下DACH1的表達(dá)沉默通過(guò)激活TGF-b信號(hào)通路促進(jìn)胃癌的侵襲轉(zhuǎn)移 閆文姬; 吳孔明; 楊云生; 郭明洲 中國(guó)腫瘤內(nèi)科進(jìn)展 中國(guó)腫瘤醫(yī)師教育(2014) 2014-07-03
5 RASSF10 Suppresses Colorectal Cancer Growth by Activating P53 Signaling and Sensitizes Colorectal Cancer Cell to Docetaxel 郭靜; 楊雅閣; 楊云生; 詹啟敏; James G.Herman; Malcolm V.Brock; 張炳勇; 郭明洲 中國(guó)腫瘤內(nèi)科進(jìn)展 中國(guó)腫瘤醫(yī)師教育(2014) 2014-07-03
6 bcl6b基因轉(zhuǎn)染對(duì)人食管癌細(xì)胞生物學(xué)行為的影響 胡隨; 毛高平; 郭明洲 世界華人消化雜志 2014-06-28
7 嗜酸粒細(xì)胞性胃腸炎臨床特點(diǎn)分析 郭靜; 孫成都; 王永華; 柴國(guó)君; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2014-06-20
8 13例以下消化道出血為主要表現(xiàn)的NSAIDs腸病臨床分析 郭靜; 孫成都; 柴國(guó)君; 孫剛; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2014-06-20
9 134例賁門息肉患者內(nèi)鏡及病理特征研究 孫成都; 范開春; 郭明洲; 王永華 胃腸病學(xué)和肝病學(xué)雜志 2014-06-20
10 血清CA125在肝硬化患者中的臨床意義及相關(guān)因素研究 孫成都; 孫剛; 郭明洲; 江華 胃腸病學(xué)和肝病學(xué)雜志 2014-05-20
11 抑癌基因啟動(dòng)子區(qū)甲基化在食管鱗狀細(xì)胞癌診斷、治療和預(yù)后中的應(yīng)用價(jià)值 吳亮; 李聞; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2014-04-20
12 啟動(dòng)子區(qū)甲基化導(dǎo)致ZNF331在結(jié)直腸癌中表達(dá)缺失 張晶芳; 楊雅閣; 郭明洲; 張炳勇 醫(yī)學(xué)與哲學(xué)(B) 2013-05-23
13 內(nèi)鏡黏膜下剝離術(shù)對(duì)治療早期胃癌的臨床應(yīng)用價(jià)值 崔盈盈; 盧忠生; 令狐恩強(qiáng); 郭明洲; 王淑芳; 楊競(jìng); 王向東; 孟江云 胃腸病學(xué)和肝病學(xué)雜志 2013-04-20
14 內(nèi)鏡黏膜下剝離食管鱗狀細(xì)胞瘤變 崔盈盈; 盧忠生; 令狐恩強(qiáng); 郭明洲; 王向東; 孟江云 胃腸病學(xué)和肝病學(xué)雜志 2013-04-20
15 啟動(dòng)子區(qū)甲基化對(duì)肝細(xì)胞癌鋅指蛋白331表達(dá)的調(diào)控 楊志華; 郭明洲; 李鑫; 毛高平 世界華人消化雜志 2013-03-28
16 食管鱗狀細(xì)胞癌細(xì)胞及組織中鈣敏感受體基因啟動(dòng)子區(qū)甲基化狀態(tài)檢測(cè) 景坤玉; 董騰慧; 郭明洲; 薛樂(lè)勛 鄭州大學(xué)學(xué)報(bào)(醫(yī)學(xué)版) 2013-03-20
17 水通道蛋白8基因3’-非翻譯區(qū)熒光素酶報(bào)告載體的構(gòu)建及其活性鑒定 閔敏; 彭麗華; 郭明洲; 楊云生 細(xì)胞與分子免疫學(xué)雜志 2012-08-18
18 人臍帶間充質(zhì)干細(xì)胞體外培養(yǎng)過(guò)程中的表觀遺傳學(xué)改變 張憲毅; 李強(qiáng); 潘瑩瑩; 侯艷; 李煜; 郭明洲; 葉穎 胃腸病學(xué)和肝病學(xué)雜志 2012-06-20
19 7例肝淀粉樣變性的臨床分析 閆文姬; 羅小洋; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2012-04-20
20 肝癌中轉(zhuǎn)化生長(zhǎng)因子(TGF)-β信號(hào)轉(zhuǎn)導(dǎo)通路的研究進(jìn)展 朱宏斌; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2012-03-20
21 表觀遺傳學(xué)變化在胃癌診斷和預(yù)后中的應(yīng)用 張?chǎng)? 陳香宇; 郭明洲; 段芳齡 胃腸病學(xué)和肝病學(xué)雜志 2012-01-20
22 MicroRNAs與炎癥性腸病 閔敏; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2012-01-20
23 人Dact2基因真核表達(dá)載體的構(gòu)建及其在結(jié)腸癌細(xì)胞中的表達(dá) 張曉梅; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2011-10-20
24 模擬失重對(duì)大鼠小腸黏膜緊密連接蛋白表達(dá)的影響` 陳英; 楊春敏; 毛高平; 王萍; 劉慶森; 郭明洲 航天醫(yī)學(xué)與醫(yī)學(xué)工程 2011-10-15
25 A型肉毒毒素治療消化道動(dòng)力性疾病的新進(jìn)展 陳英; 劉慶森; 楊云生; 楊春敏; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2011-08-20
26 肝硬化患者血漿中AFP、PKM2和ALB mRNA的檢測(cè)與分析 曲秋月; 于源滋; 李杰; 付漢江; 鐵軼; 郭明洲; 鄭曉飛 軍事醫(yī)學(xué) 2011-07-25
27 表觀遺傳學(xué)在胃癌中的應(yīng)用價(jià)值 李亞卓; 郭明洲; 趙坡 胃腸病學(xué)和肝病學(xué)雜志 2011-07-20
28 A型肉毒毒素胃壁注射對(duì)大鼠胃排空和胃肌電的影響 陳英; 劉慶森; 郭明洲; 劉文徽 胃腸病學(xué) 2011-05-25
29 非編碼RNA與消化系統(tǒng)疾病的關(guān)系 王巍峰; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2011-04-20
30 DNA甲基化在結(jié)直腸癌診療中的應(yīng)用前景 景坤玉; 薛樂(lè)勛; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2011-03-20
31 Effects of Simulated Weightlessness on Tight Junction Protein Occludin and Zonula Occluden-1 Expression Levels in the Intestinal Mucosa of Rats 陳英; 楊春敏; 劉慶森; 郭明洲; 楊云生; 毛高平; 王萍 Journal of Huazhong University of Science and Technology(Medical Sciences) 2011-02-15
32 美長(zhǎng)安聯(lián)合舒麗啟能或/和賽樂(lè)特治療腹瀉型腸易激綜合征的隨機(jī)對(duì)照性研究 范開春; 王娟; 李貞; 郭明洲; 楊云生 胃腸病學(xué)和肝病學(xué)雜志 2011-01-20
33 原發(fā)性胃惡性淋巴瘤54例胃鏡與臨床分析 溫靜; 宋捷; 李慧; 梁浩; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2010-08-20
34 肝臟囊腺瘤的臨床特征附8例臨床分析 郝雯穎; 郭明洲; 劉斌; 梁浩 胃腸病學(xué)和肝病學(xué)雜志 2010-07-20
35 原發(fā)性大腸惡性淋巴瘤臨床表現(xiàn)、內(nèi)鏡與病理特點(diǎn) 溫靜; 梁浩; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2010-07-20
36 食管胃靜脈曲張內(nèi)鏡治療對(duì)肝功能的影響 王曉燕; 毛永平; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2010-05-20
37 消化道毛細(xì)血管擴(kuò)張癥的臨床特征分析 張曉梅; 郭明洲; 楊云生 胃腸病學(xué)和肝病學(xué)雜志 2010-05-20
38 腫瘤相關(guān)蛋白NGAL的生物學(xué)特征 蔣奶貴; 許麗艷; 郭明洲; 李恩民 胃腸病學(xué)和肝病學(xué)雜志 2010-04-20
39 乳果糖預(yù)防消化道出血后誘發(fā)肝性腦病的療效觀察 溫靜; 梁浩; 常宇峰; 彭麗花; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2010-04-20
40 BRCA1啟動(dòng)子甲基化與肝癌的關(guān)系研究 張曉梅; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2010-04-20
41 肝癌的表觀遺傳學(xué)特征及其臨床意義 鞏艷; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2010-04-20
42 MicroRNAs在胃腸道疾病發(fā)生中的調(diào)控作用及其機(jī)制 彭麗華; 郭明洲; 楊云生 胃腸病學(xué)和肝病學(xué)雜志 2010-04-20
43 宿主免疫基因多態(tài)性與幽門螺桿菌感染相關(guān)疾病的關(guān)系 郝雯穎; 郭明洲; 梁浩 胃腸病學(xué)和肝病學(xué)雜志 2010-04-20
44 模擬失重對(duì)大鼠動(dòng)脈血胃動(dòng)素和一氧化氮的影響 陳英; 楊春敏; 毛高平; 孫小麗; 任曲; 占志; 郭明洲 胃腸病學(xué) 2010-01-25
45 蛋白酶體抑制劑Bortezomib對(duì)NK細(xì)胞殺傷肝癌細(xì)胞活性的影響 魏莉; 王亞?wèn)|; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2009-10-20
46 H指數(shù)應(yīng)用進(jìn)展 張偉杰; 朱濤; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2009-09-20
47 共聚焦激光顯微內(nèi)鏡對(duì)Barrett食管診斷價(jià)值的研究 黃錦; 楊云生; 韋立新; 盧忠生; 王淑芳; 孫剛; 彭麗華; 令狐恩強(qiáng); 郭明洲 第三軍醫(yī)大學(xué)學(xué)報(bào) 2009-08-30
48 Cronkhite-Canada綜合征2例報(bào)告并國(guó)內(nèi)外文獻(xiàn)評(píng)價(jià) 賈巖; 孫剛; 郭明洲; 楊云生 胃腸病學(xué)和肝病學(xué)雜志 2009-07-20
49 共聚焦顯微內(nèi)鏡對(duì)胃黏膜萎縮伴腸上皮化生的診斷價(jià)值 王淑芳; 楊云生; 韋立新; 黃錦; 孟江云; 彭麗華; 孫剛; 盧忠生; 李明陽(yáng); 令狐恩強(qiáng); 郭明洲 軍醫(yī)進(jìn)修學(xué)院學(xué)報(bào) 2009-06-28
50 食管癌的表觀遺傳學(xué)特征 黃錦; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2009-06-20
51 MicroRNAs的表觀遺傳學(xué)調(diào)控機(jī)制及其在肝癌中的表達(dá)特征 張曉梅; 楊云生; 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 2009-03-20
52 胃癌的表觀遺傳學(xué)研究 賈巖; 郭明洲; 楊云生 胃腸病學(xué)和肝病學(xué)雜志 2009-02-20
53 高爐煤氣鍋爐的設(shè)計(jì) 王華鋒; 郭明洲; 白紅彬 煤氣與熱力 2008-01-15
54 食管鱗癌雌激素受體α基因啟動(dòng)子甲基化異常 杜季梅; 李曉明; 郭明洲; 石爽; 李杰; 莊輝; 魯鳳民 國(guó)際遺傳學(xué)雜志 2006-12-15
55 食管鱗癌分泌素-3A1基因啟動(dòng)子甲基化異常 劉霜; 郭明洲; 李建生; 段芳齡; 魯鳳民 國(guó)際遺傳學(xué)雜志 2006-02-15
56 食管癌組織和非癌組織中差異基因分析和GST-π mRNA的表達(dá) 徐峰; 趙立群; 郭明洲 中華消化雜志 2002-01-30
57 RAI,one candidate gene associated with differentiation of human lung adenocarcinoma cells 王雪皎; 張睿; 劉芝華; 王秀琴; 丁芳; 郭明洲; 吳旻 Science in China(Series C:Life Sciences) 2000-10-15
58 RAI──一候選的人肺腺癌分化相關(guān)基因 王雪皎; 張睿; 王秀琴; 丁芳; 郭明洲; 劉芝華; 吳旻 中國(guó)科學(xué)C輯:生命科學(xué) 2000-06-25
59 介紹一種基因分離的新方法 于振濤; 郭明洲; 張睿; 王雪皎; 王秀琴; 吳旻 中國(guó)腫瘤臨床 2000-06-20
60 N-乙基馬來(lái)酰亞胺敏感因子NSF與食管鱗癌細(xì)胞分化有關(guān) 張睿; 王雪皎; 王秀琴; 周傳農(nóng); 丁芳; 郭明洲; 劉芝華; 吳? 癌癥 2000-05-05
61 全反式維甲酸對(duì)人細(xì)胞線粒體基因表達(dá)的調(diào)控 張睿; 王雪皎; 王秀琴; 郭明洲; 丁芳; 劉芝華; 吳旻 中國(guó)腫瘤生物治療雜志 2000-03-30
62 應(yīng)用改良AP-PCR技術(shù)進(jìn)行食管癌相關(guān)基因分析 趙立群; 徐峰; 郭明洲 河南腫瘤學(xué)雜志 2000-02-20
63 全反式維甲酸激活人肺腺癌細(xì)胞系GLC-82中-PIG-B高度同源基因—PIGB1 王雪皎; 王秀琴; 張睿; 丁芳; 郭明洲; 劉芝華; 于振濤; 吳旻 癌癥 1999-12-05
64 全反式維甲酸激活的人肺腺癌細(xì)胞基因的篩選 王雪皎; 張睿; 王秀琴; 郭明洲; 蔡巖; 丁芳; 王明榮; 黎伯銓; 吳旻 中國(guó)腫瘤臨床 1999-02-20
65 維甲酸激活表達(dá)的人肺腺癌細(xì)胞分化相關(guān)基因的篩選 王雪皎; 王秀琴; 蔡巖; 王明榮; 黎伯銓; 丁芳; 張睿; 郭明洲; 林晨; 吳旻 自然科學(xué)進(jìn)展 1998-12-15
66 食管癌相關(guān)基因的分離和序列測(cè)定 郭明洲; 易粹瓊; 侯曉華; 王秀琴; 張睿 衛(wèi)生毒理學(xué)雜志 1998-06-25
67 林縣食管癌組織和非癌食管組織差異DNA片段的克隆研究 郭明洲; 劉霜; 王秀琴; 易粹瓊; 侯曉華; 吳衛(wèi)東; 王雪皎; 張睿; 魯鳳民; 劉芝華; 吳? 中華預(yù)防醫(yī)學(xué)雜志 1998-05-25
68 危重病患者血腫瘤壞死因子和白細(xì)胞介素6水平的研究 張炳勇; 張文武; 馬改風(fēng); 伍學(xué)強(qiáng); 楊淑香; 張善亮; 郭明洲 中國(guó)急救醫(yī)學(xué) 1995-07-25
69 實(shí)驗(yàn)性動(dòng)脈粥樣硬化兔血小板胞漿游離鈣和鈣泵的變化 鄭麗麗; 閻西艴; 韓萍; 葉啟霞; 郭明洲 中華心血管病雜志 1995-04-28
70 肝細(xì)胞刺激再生因子對(duì)大鼠實(shí)驗(yàn)性肝損傷的療效及作用機(jī)制的研究 郭明洲; 段芳齡; 郭宏濤; 楊惠芳; 王躍勤; 虎建恩 臨床消化病雜志 1992-05-15
71 肝細(xì)胞再生剌激因子與肝損傷的修復(fù) 郭明洲 胃腸病學(xué)和肝病學(xué)雜志 1992-04-01
72 鍺-132對(duì)二甲基肼誘導(dǎo)小鼠結(jié)腸隱窩上皮細(xì)胞微核及凋謝的拮抗作用 郭明洲; 段芳齡; 孫含笑; 楊慧芳; 王躍勤; 虎建恩 胃腸病學(xué)和肝病學(xué)雜志 1992-04-01